{"id":"PYSEC-2026-2777","summary":"Open Babel has uninitialized pointer dereference in PQS pFormat","details":"### Summary\n\nA memory-safety vulnerability in Open Babel's PQS parser caused an\nuninitialized pointer dereference when reading a crafted input file.\n\n### Details\n\nThe flaw was in the `pFormat` handling of the PQS reader. A malformed\ninput caused the parser to dereference a format pointer that had\nnever been initialized.\n\n### Impact\n\nOpen Babel is a C++ library and CLI used to read and write chemistry\nfile formats; it is shipped by Linux distributions and embedded in\nservices that may parse untrusted input. Triggering this vulnerability\nrequires the victim to open a malicious PQS file with the `obabel`\ntool, the `OBConversion` API, or any of the language bindings (Python,\nRuby, Java, R, Perl, C#, PHP).\n\n### Affected versions\n\nAll releases up to and including 3.1.1.\n\n### Patched version\n\n3.2.0 (released 2026-05-26).\n\n### Patch\n\nFix commit: https://github.com/openbabel/openbabel/commit/2a7d2cda\n\nA minimized reproducer for this CVE is checked in under\n`test/files/fuzz_regress/` and is exercised on every CI build under\nASAN+UBSAN by the `fuzzregresstest` harness.\n\n### Credit\n\nReported by Cisco TALOS.","aliases":["CVE-2022-46280","GHSA-8qxc-57hf-hc9j"],"modified":"2026-07-13T16:32:07.088343968Z","published":"2026-07-13T15:46:26.292464Z","references":[{"type":"WEB","url":"https://github.com/openbabel/openbabel/security/advisories/GHSA-8qxc-57hf-hc9j"},{"type":"ADVISORY","url":"https://nvd.nist.gov/vuln/detail/CVE-2022-46280"},{"type":"WEB","url":"https://github.com/openbabel/openbabel/commit/2a7d2cda8bd47daade2e555e34b69651a2e132ef"},{"type":"PACKAGE","url":"https://github.com/openbabel/openbabel"},{"type":"WEB","url":"https://talosintelligence.com/vulnerability_reports/TALOS-2022-1670"},{"type":"WEB","url":"https://www.talosintelligence.com/vulnerability_reports/TALOS-2022-1670"},{"type":"PACKAGE","url":"https://pypi.org/project/openbabel"},{"type":"ADVISORY","url":"https://github.com/advisories/GHSA-8qxc-57hf-hc9j"}],"affected":[{"package":{"name":"openbabel","ecosystem":"PyPI","purl":"pkg:pypi/openbabel"},"ranges":[{"type":"ECOSYSTEM","events":[{"introduced":"0"},{"fixed":"3.2.0"}]}],"versions":["1.8","1.8.1","1.8.2","1.8.3","1.8.4","2.4.0","2.4.1","3.0.0","3.0.0a1","3.1.1","3.1.1.1"],"database_specific":{"source":"https://github.com/pypa/advisory-database/blob/main/vulns/openbabel/PYSEC-2026-2777.yaml"}}],"schema_version":"1.7.5","severity":[{"type":"CVSS_V3","score":"CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H"}]}